
Niacinamide is the talk of the town as a possible skincare miracle ingredient. This component is essentially a type of vitamin B3, and is a popular ingredient in a range of commercial skincare formulations. However, most people don’t really know what niacinamide is exactly and what it can fo for our skin. Let’s review this so-called wonder ingredient, and how it works, so you can decide whether these products are for you!
What is Niacinamide?
- Vitamin B3 has two major forms:
i. Niacin
ii. Nicotine acid
Niacinamide is also known as niacin, as well as nicotinamide. It is famous for its possible uses in treating damaged skin, rosacea, acne, wrinkles, and pigmentation. The question is, does science confirm these claims? The answer from the scientists is not entirely clear, but scientific research does support the powers of niacinamide to some extent.
To them, niacin is the base of the highly significant biochemical cofactors (NADP+ and NADH/NAD+ molecules). These molecules are mandatory for the chemical reaction skin cells and all human cells need for damage repair, better functionality, and propagation. Niacinamide is necessary for the production of NAD+ which is essential for a number of chemical reactions that are beneficiary to our cells.
Should I Use Niacinamide?
If niacin already exists in the human body, why do we care about its intake? Research is ongoing, but based on the existing studies, there is some evidence that niacinamide could speed up the process of neutralising free radicals and regenerating healthy cells.

Free radicals are those unstable and highly reactive molecules that have gained or lost an electron. If left unattended, they can damage healthy cells. NAD+ neutralises free radicals by pairing free radicals with an electron. Some studies have found that topical niacinamide contributes to the production of skin-protective lipids called ceramides. This may be the reason behind the anti-ageing properties of niacinamide.
It is important to note that niacinamide contributes to some of the most of the significant functions relating to cell health. However, this does not mean that niacinamide can cure everything related to cell disorders. This is why you must consult a dermatologist before buying or using any skincare product, including those containing niacinamide, and always use products from quality brands like Luminositie.
Does Niacinamide Prevent Skin Cancer?
In a study published in the New England Journal of Medicine, 386 participants had a 5-year history of at least a couple of non-melanoma skin cancers. They were served with oral niacinamide (500mg twice a day) or a placebo for one year. The occurrence of new cases was 23% less in the patients who received oral niacinamide in comparison to the occurrence of new cases in the patients who received placebo.
However, the researchers in this study never concluded that niacinamide can prevent skin cancer for the rest of your life. Another important factor to note is that all of those participants had a history of skin cancer so it is difficult to conclude whether it can prevent skin cancer in people with no history of skin cancer. Extensive research is still required, but the signs are hopeful for those who already have a history of non-melanoma skin cancer.
Does Niacinamide have any Side Effects?
The intake of niacinamide by mouth is safer for adults but it is still better to consult with an expert starting any new routine. They will be able to recommend the most suitable for you. The possible side effects of niacinamide incude:
- Rashes and itching
- Dizziness
- Gas
- Stomach upset
- High blood sugar (if consumed more than 3 grams per day)
In general terms, the ideal doseof niacinamide for adults is up to 35mg (per day) to minimise possible side effects. High blood sugar can be a side effect if you take over three grams of niacinamide per day. The application of niacinamide to the skin may result in itching, mild burning, and redness in the skin, but this is likely to lessen over time.
Getting Started with Niacinamide
There are only very low risks associated with a skin-care routine featuring topical niacinamide. Look for a reliable product that contains a the correct amount of niacinamide. In the beginning, some people may experience signs of itching and burning but for most people these fade away over time. However, if symptoms persist, consult your doctor or dermatologist.
The ideal concentration of niacinamide in topical formulations ranges from 2% to 10%. Niacinamide can be helpful to keep your skin healthy and reduce wrinkles and signs of ageing. It can fight acne to some extent and can help you look young.
Sometimes the wrong diagnosis or the wrong product and cause more problems than solutions. Niacinamide can be great for some people, but it may not address all your issues. Do consult your dermatologist and be sure to follow their recommendations.
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